Metformin For Weight Loss In PCOS: Is It A Promising Solution?

Nimisha Gupta

Nimisha Gupta
Jul 2023

2 min read
Metformin For Weight Loss In PCOS

Table of content

Are you tired of struggling with weight gain and the frustrating symptoms of PCOS? If so, you’re not alone. Polycystic Ovary Syndrome (PCOS) affects millions of women worldwide, causing hormonal imbalances that lead to weight gain, irregular periods, and even difficulty conceiving. But have you heard of a medication named Metformin for weight loss in PCOS?

Enter Metformin – a medication commonly prescribed for managing diabetes but also gaining attention as a potential tool for weight loss in PCOS. In this blog post, we’ll explore the effectiveness and safety of Metformin in tackling weight issues associated with PCOS. So keep reading to discover if this could be the breakthrough you’ve been waiting for!

CTA ImageCTA Image

Understanding PCOS And Its Association With Weight Gain

PCOS, short for Polycystic Ovary Syndrome, is a common hormonal disorder that affects women of reproductive age. It occurs when the ovaries produce excess androgens (male hormones) instead of the normal balance of estrogen and progesterone. This hormonal imbalance affects the ovaries and can lead to complications such as irregular or skipped periods, excess body hair, acne, pelvic pain, difficulty getting pregnant, and other symptoms. So, the characteristics Of PCOS are:

1. Cysts In The Ovaries

One of the primary characteristics of PCOS is the formation of tiny cysts on the ovaries. These cysts are actually follicles that have failed to release an egg during ovulation. As a result, menstrual cycles become irregular or absent altogether.

2. Weight Gain

Women with PCOS often have elevated levels of insulin, a hormone that regulates blood sugar. It can lead to high production of androgens (male hormones) and disrupt the balance of other hormones. These hormonal imbalances can contribute to weight gain, especially in the abdominal area. Additionally, insulin resistance makes it harder for the body to utilize glucose for energy, leading to higher blood sugar levels and increased fat storage. The combination of hormonal imbalances, insulin resistance, and metabolic changes in PCOS can make weight management more challenging for affected individuals.

3. High Levels Of Male Hormones (Androgen)

PCOS can make the body produce too much of a hormone called androgen, usually present in small amounts in women. It can result in excess facial and body hair, acne, male-pattern baldness, and other signs of hyperandrogenism.

4. High Risk Of Long Term Health Issues

Besides physical manifestations like acne, excessive hair growth (hirsutism), and thinning scalp hair, PCOS also triggers the risk of chronic diseases such as type 2 diabetes, infertility, high blood pressure, and heart disease. For infertility, you can also go through our fertility diet plan for better results.

5. Insulin Resistance

PCOS can also affect how the body uses a hormone called insulin that helps cells use sugar for energy. If cells become resistant to insulin, blood sugar levels can rise, and the body may make more insulin to try to lower them. Too much insulin can also stimulate the ovaries to make more androgen.

While there isn’t a cure for PCOS, there are ways to manage its symptoms effectively – one potential method being Metformin. So let’s delve into what exactly this medication is and how it could help those struggling with weight loss in PCOS.

Metformin For Weight Loss In PCOS: How It Works?

Metformin is a medication that has gained significant attention in PCOS (Polycystic Ovary Syndrome) and weight loss. But what exactly is Metformin? Let’s get into the details.

Metformin relates to a class of medications called biguanides, commonly used to treat type 2 diabetes. However, it has garnered attention as a potential solution for weight loss in women with polycystic ovary syndrome (PCOS). But how exactly does Metformin work its magic? Let’s see how it works:

1. Improving Insulin Sensitivity

In PCOS, the body’s cells become resistant to insulin, leading to elevated insulin levels. This hormonal imbalance contributes to weight gain and difficulty losing excess pounds. Metformin improves the body’s response to insulin, helping lower blood sugar levels and reducing insulin production. It can lead to decreased hunger, reduced food intake, and improved weight management.

2. Reducing Appetite

By targeting insulin resistance, Metformin indirectly aids in weight loss for individuals with PCOS. It helps regulate glucose metabolism and decrease appetite while increasing feelings of fullness after meals. Metformin may influence the brain’s appetite-regulating centers, leading to decreased appetite and cravings. This effect can help individuals with PCOS consume fewer calories and make healthier food choices, supporting weight loss efforts and improving overall metabolic function.

3. Modifying Hormonal Imbalances

Moreover, studies have shown that Metformin may also help lower the Androgen levels in women with PCOS. High androgen levels are often responsible for symptoms such as excessive hair growth and acne. Thus, Metformin may be the solution for how to lose weight with PCOS by addressing this underlying hormone imbalance, as androgens lead to weight gain, particularly in the abdominal area.

Now how much weight can you lose with Metformin for PCOS? Well, the weight loss achieved with Metformin in PCOS can vary from person to person. Studies have shown that Metformin, combined with lifestyle changes, may contribute to a modest weight loss of around 5-10% of body weight. However, individual results can differ depending on factors such as adherence to medication, dietary modifications, exercise habits, and overall health status.

Similarly, if you ask how long does it take for Metformin to work for PCOS weight loss? Or how fast do you lose weight on Metformin? For this, we would say that the time it takes for Metformin to work for weight loss in PCOS varies among individuals. Some people may start to see changes in weight within a few weeks of starting treatment, while others may take several months. It is important to note that Metformin is not a quick-fix solution and works best when combined with lifestyle modifications such as a healthy diet plan for weight loss and regular exercise.

It is important to note that while many women experience positive outcomes from taking Metformin for weight loss in PCOS, individual results may vary. Additionally, consulting with a doctor is always recommended before starting any new medication or treatment plan.

Benefits Of Taking Metformin For Weight Loss In PCOS

Taking metformin for weight loss in PCOS may offer several potential benefits, including:

  • Control Blood Sugar: Metformin helps improve insulin sensitivity, manage blood sugar levels, and reduce insulin resistance commonly associated with PCOS. This can support weight loss efforts and help manage symptoms related to insulin dysregulation.
  • Weight Reduction: Metformin, combined with daily workouts and a balanced diet, may contribute to modest weight loss in individuals with PCOS. It can aid in reducing overall body weight and body mass index (BMI).
  • Hormonal Balance: Metformin has the potential to help restore hormonal balance in individuals with PCOS. It may lower androgen (male hormone) levels, leading to improved regulation of the menstrual cycle and reduced symptoms like excessive hair growth and acne.
  • Improved Cholesterol Profile: Metformin has shown the potential to improve lipid profiles in individuals with PCOS. It may help maintain normal cholesterol levels by reducing LDL (bad) cholesterol levels and increasing HDL (good) cholesterol levels. These improvements in cholesterol levels can contribute to improved cardio health and lower the risk of heart disease.
  • Appetite Control: Some individuals experience reduced appetite while taking metformin, which can support adherence to a calorie-controlled diet and facilitate weight loss.
  • Improved Fertility: Weight loss achieved with metformin in PCOS may positively impact fertility outcomes. By addressing underlying hormonal imbalances, regulating menstrual cycles, and promoting regular ovulation, metformin can enhance the chances of conception in females trying to conceive.

However, individual responses to Metformin may vary, and its efficacy for weight loss in PCOS can depend on factors such as adherence to medication, lifestyle modifications, and overall health status.

Risks Associated With Metformin For Weight Loss In PCOS

Metformin, a commonly prescribed medication for PCOS, is known to have some potential side effects. While it can be highly effective in managing insulin resistance and aiding weight loss, it’s essential to be aware of possible adverse reactions.

  • Gastrointestinal Issues: This may include stomach pain, diarrhea, nausea, abdominal discomfort, loss of appetite, or vomiting. These discomforts are usually temporary and subside as the body adjusts to the medication.
  • Vitamin B12 Deficiency: Long-term use of Metformin can affect vitamin B12 absorption, leading to a deficiency. Regular monitoring of vitamin B12 levels and necessary supplementation can help mitigate this risk. Check out these Vitamin B12-rich foods and include them in your diet.
  • Lactic Acidosis (Rare): While rare, lactic acidosis is a serious but potentially life-threatening side effect of Metformin. It is more likely to occur in individuals with kidney or liver problems, excessive alcohol consumption, or conditions that can lead to reduced oxygen delivery to tissues.
  • Hypoglycemia (Low Blood Sugar): Metformin does not typically cause hypoglycemia, but when taken with other blood sugar-lowering medications or inappropriately with meals, it can increase the risk of hypoglycemia.
  • This may Lead To Increased Weight In Children born from mothers who took Metformin during pregnancy. However, it’s important to note that more research is needed to understand this potential association fully.

Also, you must know that everyone reacts differently to medications. Some people may experience minimal or no side effects while taking Metformin for PCOS management. If you’re considering Metformin as part of your PCOS weight loss plan, consult your healthcare provider about its potential benefits and risks specific to your situation. They will guide you on proper dosage and any necessary precautions based on your medical history.

Taking Metformin For Weight Loss In PCOS: Points To Consider

While taking Metformin for weight loss in PCOS, it is important to consider the following:

1. Consult with a Healthcare Professional

Work closely with your healthcare professional to determine the appropriate dosage and duration of metformin treatment for weight management in PCOS. They will provide guidance tailored to your individual needs.

2. Follow The Prescribed Dosage

Take Metformin exactly as prescribed by your healthcare professional. Do not exceed or skip doses unless advised otherwise.

3. Balanced Macronutrients

Focus on a well-balanced diet with adequate lean protein, healthy fats, fiber-rich foods, and complex carbohydrates. It can help provide sustained energy and support overall health.

4. Portion Control

Be mindful of portion sizes to consume appropriate calories for weight loss. Consider using smaller plates or tracking your food intake to help monitor portions.

5. Limit Added Sugars

Minimize the intake of foods and beverages high in added sugars, as they can lead to blood sugar spikes and hinder weight loss efforts.

6. Combine with Healthy Lifestyle Changes

Metformin works best with lifestyle modifications such as a balanced diet and regular exercise. Adopting a healthy food chart and engaging in physical activity can enhance the effects of Metformin for weight loss.

7. Regular Monitoring

Stay in touch with your healthcare professional for regular check-ups to monitor your progress and any potential side effects. They may recommend blood tests or other assessments to evaluate your response to Metformin.

8. Be Aware of Potential Side Effects

Metformin can also have side effects. Common side effects may include gastrointestinal issues such as nausea, diarrhea, or stomach discomfort. If you experience persistent or severe side effects, inform your healthcare professional.

9. Stay Hydrated

Drink plenty of water while taking Metformin to stay hydrated and support overall health. You can check our blog on mustard seeds for weight loss to boost your metabolism.

10. Be Mindful of Other Medications

Inform your healthcare professional about all your medications, herbal products, or supplements, as they may interact with Metformin. It includes both prescription and over-the-counter medications.

11. Pregnancy and Breastfeeding

If you are pregnant or planning to become pregnant or a  breastfeeding mother, discuss with your healthcare professional before taking Metformin, as its use during these periods may require special considerations.

Don’t forget the importance of contacting a registered dietitian or healthcare professional for expert advice on your diet. They can provide personalized recommendations that suit your specific needs and goals. With their help, you can create a well-rounded and balanced PCOS diet chart for weight loss that works hand in hand with your metformin treatment. So why not tap into their expertise and get the support you need to succeed?

Conclusion – Is Metformin A Promising Solution For Weight Loss In PCOS?

PCOS, or Polycystic Ovary Syndrome, affects millions of women worldwide through hormonal imbalances that can lead to weight gain and difficulty losing weight. This is where Metformin comes into play. It has gained significant attention as a potential solution for weight loss in women with PCOS. But should PCOS patients take Metformin? 

Generally, Metformin is used to treat Type 2 diabetes, but it is also helping women with PCOS shed those stubborn pounds. Its main mechanism of action is improving insulin sensitivity and reducing insulin resistance, which are often underlying factors contributing to weight gain in PCOS.

While studies have supported the use of Metformin for weight loss in PCOS, it’s important to note that results may vary from person to person. Additionally, like any medication, there are potential side effects associated with its use, like nausea, diarrhea, and stomach cramps. While some individuals may experience significant weight loss with Metformin alone, others may require additional lifestyle changes, such as a healthy diet and regular exercise routines for weight loss, to see optimal results. So, consult your doctor before starting with Metformin for weight loss in PCOS.

Megha’s Weight Loss With PCOS – Shed 10 Kgs in 55 Dyas!

Delhi-based Megha Hooda was facing weight gain issues due to her PCOS. She sought help from a PCOS weight loss specialist at Fitelo, who designed a personalized home-based diet plan, taking into account her preferences. With her dedication and following the diet plan diligently, Megha lost an impressive 10 kilograms in just 55 days! Read about Megha’s inspiring transformation below. If she can do then you also can do this!

Fun Fact

Plastic can cause PCOS!

Plastic found in everyday bottles, food containers, or cosmetics contains the most common environmental toxin BPA (Bisphenol A), potentially contributing to hormonal imbalances associated with PCOS. It is found that women with PCOS have 30% – 40% more BPA in their blood compared to women without PCOS. It also increases the amount of androgen in blood, leads to inflammation & overloads the liver. So, let’s embrace a plastic-reducing lifestyle and keep our hormones happy!

Do Women Lose Weight Slower Than Men? – Dietitian Mac Singh

One of our most asked questions is – do women lose weight slower than men? Well, the answer is yes. In this short 4-minute video, dietician Mac Singh explains how men’s and women’s bodies differ in basal metabolic rate. He also talks about how hormones play a crucial role in the way fat is stored in our bodies and how it governs weight loss. To know more, watch this complete video:

Frequently Asked Questions

How Much Weight Can You Lose With Metformin For PCOS?

Well, the weight loss achieved with Metformin in PCOS can vary from person to person. Studies have shown that Metformin, combined with lifestyle changes, may contribute to a modest weight loss of around 5-10% of body weight. However, individual results can differ depending on factors such as adherence to medication, dietary modifications, exercise habits, and overall health status.

How Long Does It Take For Metformin To Work For PCOS Weight Loss?

The time it takes for Metformin to work for weight loss in PCOS varies among individuals. Some people may start to see changes in weight within a few weeks of starting treatment, while others may take several months. It is important to note that Metformin is not a quick-fix solution and works best when combined with lifestyle modifications such as a healthy diet and regular exercise.

Does Metformin Reduce Belly Fat?

While Metformin isn’t a magic potion for melting belly fat, it can play a role in helping to reduce it. By improving insulin sensitivity, Metformin may contribute to overall weight loss, including trimming that stubborn belly fat. Remember, Metformin works best with a healthy diet, regular workouts, and other lifestyle changes.

Are There Any Specific Dietary Considerations Or Restrictions While Taking Metformin For Weight Loss In PCOS?

While no specific dietary restrictions are associated with taking Metformin, following a balanced and healthy diet is generally recommended. Focus on consuming nutrient-dense foods, managing portion sizes, and reducing the intake of processed and sugary foods. Also, consult with a registered dietitian for a personalized diet plan.

Can I Continue Taking Metformin After Achieving My Weight Loss Goals In PCOS?

The decision to continue or discontinue Metformin after achieving weight loss goals in PCOS should be made in consultation with your healthcare professional. Factors such as ongoing insulin resistance, other PCOS symptoms, and individual health considerations will be considered. Your doctor can guide whether it is appropriate to continue Metformin to manage PCOS or if other treatment options suit your situation.

CTA ImageCTA Image

Contact Us Today

Get in touch with our expert team at Fitelo to kick-start your own transformative journey! Let us guide you toward your weight loss goals and help you cultivate sustainable & healthy eating habits. So, contact us today and take the first step towards a healthier, happier you with Fitelo!


This blog post was written to help you make healthy and better food choices. So, be aware and take care. The vital thing to consider is your own health before starting a restrictive diet. Therefore, always seek advice from a doctor/dietitian before starting if you have any concerns.
Eat Healthy, Live Healthy. Enjoy a long, happy life.

No Thoughts on Metformin For Weight Loss In PCOS: Is It A Promising Solution?

Leave A Comment

The first step to a healthier you starts here. Talk to our experts now

Get access to 1000+ healthy and tasty recipes, fitness tips and more. Subscribe to our newsletter